Peter Carmeliet Selected Research

Pathologic Neovascularization

1/2020	Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
12/2017	Angiogenesis revisited from a metabolic perspective: role and therapeutic implications of endothelial cell metabolism.
5/2017	Endothelial cell metabolism: an update anno 2017.
1/2016	Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers-A New Perspective?
1/2016	Glycolytic regulation of cell rearrangement in angiogenesis.
1/2014	Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.
2/2013	The placental growth factor as a target against hepatocellular carcinoma in a diethylnitrosamine-induced mouse model.
9/2012	Inhibition of the placental growth factor decreases burden of cholangiocarcinoma and hepatocellular carcinoma in a transgenic mouse model.
5/2011	Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice.
9/2008	Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium.

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Peter Carmeliet Research Topics

Disease

89	Neoplasms (Cancer) 01/2022 - 12/2002
66	Hypoxia (Hypoxemia) 01/2022 - 02/2002
26	Inflammation (Inflammations) 10/2022 - 01/2003
21	Neoplasm Metastasis (Metastasis) 01/2022 - 11/2007
17	Pathologic Neovascularization 01/2020 - 07/2002
16	Ischemia 01/2021 - 09/2006
14	Fibrosis (Cirrhosis) 01/2022 - 05/2003
11	Atherosclerosis 01/2022 - 08/2002
9	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2016 - 01/2004
8	Sepsis (Septicemia) 01/2021 - 06/2003
8	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2010 - 08/2003
7	Infections 01/2021 - 04/2002
7	Pre-Eclampsia (Preeclampsia) 01/2019 - 03/2003
7	Necrosis 01/2017 - 12/2002
6	Breast Neoplasms (Breast Cancer) 10/2021 - 10/2013
6	Disease Progression 01/2021 - 08/2002
6	Infarction (Infarctions) 01/2021 - 04/2002
6	Wounds and Injuries (Trauma) 11/2020 - 02/2002
6	Choroidal Neovascularization 01/2020 - 04/2003
6	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 09/2012
6	Pneumonia (Pneumonitis) 01/2019 - 04/2002
6	Stroke (Strokes) 02/2016 - 02/2002
5	Body Weight (Weight, Body) 01/2021 - 01/2004
5	Myocardial Infarction 01/2019 - 01/2007
5	Heart Failure 08/2017 - 01/2005
5	Brain Ischemia (Cerebral Ischemia) 02/2016 - 04/2002
5	Edema (Dropsy) 06/2012 - 04/2002
5	Thrombosis (Thrombus) 08/2009 - 11/2003
4	Atherosclerotic Plaque (Atheroma) 01/2022 - 03/2002
4	Obesity 10/2016 - 12/2009
4	Arthritis (Polyarthritis) 04/2013 - 08/2002
4	Hypertrophy 07/2011 - 01/2005
4	Vascular Remodeling 11/2010 - 05/2003
4	Endotoxemia 10/2008 - 06/2003
4	Pneumoperitoneum 10/2004 - 07/2003
3	Medulloblastoma 01/2022 - 02/2013
3	Anemia 01/2021 - 02/2008
3	Leukemia 01/2020 - 01/2011
3	Starvation 01/2020 - 01/2005
3	Mitochondrial Diseases (Mitochondrial Disease) 10/2019 - 12/2011

Drug/Important Bio-Agent (IBA)

82	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 02/2002
41	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 01/2003
33	Oxygen (Dioxygen)IBA 01/2021 - 02/2002
25	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2022 - 02/2008
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2003
18	Plasminogen Activator Inhibitor 1IBA 07/2014 - 03/2002
12	CollagenIBA 01/2022 - 05/2003
11	Transcription Factors (Transcription Factor)IBA 01/2020 - 02/2005
11	Vascular Endothelial Growth Factor BIBA 04/2016 - 09/2003
11	Plasminogen Activators (Plasminogen Activator)IBA 04/2012 - 03/2002
10	EnzymesIBA 01/2021 - 03/2010
10	Messenger RNA (mRNA)IBA 01/2021 - 04/2003
9	CytokinesIBA 01/2019 - 01/2003
9	Tissue Plasminogen Activator (Alteplase)FDA Link 05/2014 - 12/2002
8	AntibodiesIBA 01/2018 - 03/2004
8	Bevacizumab (Avastin)FDA Link 10/2014 - 07/2004
8	PlasminogenIBA 03/2013 - 12/2002
8	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 04/2012 - 04/2002
7	Neuropilin-1IBA 01/2022 - 02/2005
7	Protein Isoforms (Isoforms)IBA 01/2021 - 02/2003
7	Prostaglandins FIBA 01/2019 - 11/2010
7	LigandsIBA 01/2018 - 04/2002
7	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 01/2016 - 10/2003
7	Plasminogen InactivatorsIBA 07/2014 - 04/2003
6	Phosphotransferases (Kinase)IBA 10/2022 - 11/2007
6	Matrix Metalloproteinases (MMPs)IBA 01/2022 - 04/2003
6	Thromboplastin (Tissue Factor)IBA 01/2021 - 01/2004
6	Pharmaceutical PreparationsIBA 01/2020 - 02/2011
6	Angiogenesis InhibitorsIBA 08/2013 - 03/2004
6	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 03/2013 - 04/2002
6	Transforming Growth Factor beta (TGF-beta)IBA 07/2009 - 12/2002
5	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2018
5	LipidsIBA 01/2021 - 11/2012
5	Peptide Hydrolases (Proteases)FDA Link 01/2013 - 03/2004
4	Dextrans (Dextran)FDA Link 10/2022 - 04/2010
4	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2022 - 01/2016
4	Monoclonal AntibodiesIBA 01/2022 - 12/2009
4	CholesterolIBA 01/2022 - 03/2004
4	matrigelIBA 10/2021 - 01/2005
4	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2005
4	AllergensIBA 10/2017 - 07/2002
4	Urokinase Plasminogen Activator ReceptorsIBA 02/2016 - 08/2003
4	Placenta Growth FactorIBA 02/2016 - 11/2009
4	FibrinIBA 03/2013 - 04/2003
4	Fibrinogen (Factor I)FDA Link 03/2013 - 04/2003
4	Apolipoproteins E (ApoE)IBA 02/2013 - 03/2002
4	ApolipoproteinsIBA 02/2013 - 03/2002
4	Immunoglobulin G (IgG)IBA 12/2009 - 02/2002
4	Carbon DioxideIBA 10/2004 - 07/2003
3	Cysteine (L-Cysteine)FDA Link 10/2022 - 08/2011
3	Small Cytoplasmic RNAIBA 01/2022 - 01/2020
3	pimonidazoleIBA 01/2021 - 04/2010
3	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 11/2015
3	Imatinib Mesylate (Gleevec)FDA Link 01/2020 - 01/2011
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 07/2014
3	Amino Acids FDA Link 01/2020 - 08/2005

Therapy/Procedure

48	Therapeutics 10/2022 - 01/2003
15	Drug Therapy (Chemotherapy) 01/2018 - 04/2003
5	Ligation 02/2016 - 12/2002
4	Lasers (Laser) 10/2007 - 04/2003